세미나 Seminars

2016.12.19 14:10

12월28일(수)대학원특별세미나 Prof. James Y. Hamilton(Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany)

?

단축키

Prev이전 문서

Next다음 문서

+ - Up Down Comment Print Files
?

단축키

Prev이전 문서

Next다음 문서

+ - Up Down Comment Print Files
Extra Form
초청강사 Prof. James Y. Hamilton
소속 Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany
일시 2016년 12월 28일(수) 오후5시
장소 아산이학관 331

“Development of a Broad Range of Asymmetric CC Bond 

Forming Reactions with a Versatile Iridium Catalyst”


 

Among the most important challenges in modern organic synthesis is the catalytic asymmetric formation of carboncarbon bonds, which can grant rapid access to molecular building blocks with potential applications in medicinal, agricultural, and materials chemistry. These transformations become particularly valuable when they exhibit high atom/step economy and operational convenience.

The presentation focuses on the versatility of a chiral iridiumphosphoramidite/olefin complex, which enables a number of enantioconvergent carboncarbon bond forming processes. Following operationally simple protocols, readily available racemic allylic alcohols or their derivatives can undergo direct displacement reactions with alkenyltrifluoroborates(C-sp2), alkynyltrifluoroborates(C-sp), allylsilanes(C-sp3), unactivated alkenes(C-sp3), and functionalized alkylzinc reagents(C-sp3). Various classes of optically active scaffolds obtained via these methods have been utilized in concise preparations of biologically active natural products and medicinal/agricultural agents.


1.png



20161228_특별세미나_Prof. James Y. Hamilton.pdf


Designed by sketchbooks.co.kr / sketchbook5 board skin

나눔글꼴 설치 안내


이 PC에는 나눔글꼴이 설치되어 있지 않습니다.

이 사이트를 나눔글꼴로 보기 위해서는
나눔글꼴을 설치해야 합니다.

설치 취소

Sketchbook5, 스케치북5

Sketchbook5, 스케치북5

Sketchbook5, 스케치북5

Sketchbook5, 스케치북5