| 첨부 '1' |
|---|
| author | Hak Joong Kim |
|---|---|
| journal | Org. Lett., 2017, 19 (3), pp 500–503 |
| Homepage | https://sites.google.com/site/kubccb/ |
Acinetobactin is a major siderophore utilized by the human pathogen Acinetobacter baumannii. The rapid acquisition of drug resistance by A. baumannii has garnered concern globally. Herein, acinetobactin and systematically generated analogues were prepared and characterized; the binding and cellular delivery of Fe(III) by the analogues were evaluated. This investigation not only led to the clarification of the physiologically relevant acinetobactin structure but also revealed several key structural elements for its functionality as a siderophore.
http://pubs.acs.org/doi/abs/10.1021/acs.orglett.6b03671?journalCode=orlef7&
Multiplexed Post-Experimental Monoisotopic Mass Refinement (m...
Cobalt Assisted Synthesis of IrCu Hollow Octahedral Nanocages...
-
Read More
Ultrafast fluxional exchange dynamics in electrolyte solvation sheath of lithium ion battery
Lithium cation is the charge carrier in lithium-ion battery. Electrolyte solution in lithium-ion battery is usually based on mixed solvents consisting of polar carbonates with different aliphatic chains. Despite various experimental evidence... -
Read More
Molecular design of a wide-band-gap conjugated polymer for efficient fullerene-free polymer solar cells
Two p-type conjugated polymers with disparate optical and electronic properties, PB3T and PB2T, were developed and applied in fullerene-free polymer solar cells (PSCs). The photovoltaic performance of the PB3T-based PSC device processed by a... -
Read More
Multiplexed Post-Experimental Monoisotopic Mass Refinement (mPE-MMR) to Increase Sensitivity and Accuracy in Peptide Identifications from Tandem Mass Spectra of Cofragmentation
Mass spectrometry (MS)-based proteomics, which uses high-resolution hybrid mass spectrometers such as the quadrupole-orbitrap mass spectrometer, can yield tens of thousands of tandem mass (MS/MS) spectra of high resolution during a routine b... -
Read More
Key Structural Elements for Cellular Uptake of Acinetobactin, a Major Siderophore of Acinetobacter baumannii
Acinetobactin is a major siderophore utilized by the human pathogen Acinetobacter baumannii. The rapid acquisition of drug resistance by A. baumannii has garnered concern globally. Herein, acinetobactin and systematically generated analogues... -
Read More
Cobalt Assisted Synthesis of IrCu Hollow Octahedral Nanocages as Highly Active Electrocatalysts toward Oxygen Evolution Reaction
Development of oxygen evolution reaction (OER) catalysts with reduced precious metal content while enhancing catalytic performance has been of pivotal importance in cost-effective design of acid polymer electrolyte membrane water electrolyze... -
Read More
Singly and Doubly Occupied Higher Quantum State in Nanocrystals
Filling the lowest quantum state of the conduction band (CB) of colloidal nanocrystals with a single electron, which is analogous to the filling the lowest unoccupied molecular orbital (LUMO) in a molecule with a single electron, has attract... -
Read More
Cost-Effective, High-Performance Porous-Organic-Polymer Conductors Functionalized with Sulfonic Acid Groups by Direct Postsynthetic Substitution
We demonstrate the facile microwave-assisted synthesis of a porous organic framework 1 and the sulfonated solid (1S) through postsubstitution. Remarkably, the conductivity of 1S showed an approximately 300-fold enhancement at 30 °C as compar... -
Read More
Liposomal Texaphyrin Theranostics for Metastatic Liver Cancer
Reported here is a new theranostic agent, 1, which consists of a Gd3+-texaphyrin core conjugated to a doxorubicin prodrug via a disulfide bond. Conjugate 1 was designed to undergo cleavage in the presence of glutathione (GSH), a species typi... -
Read More
Water Dynamics in Cytoplasm-Like Crowded Environment Correlates with the Conformational Transition of the Macromolecular Crowder
Polyethylene glycol (PEG) is a unique polymer material with enormous applicability in many industrial and scientific fields. Here, its use as macromolecular crowder to mimic the cellular environment in vitro is the focus of the present study... -
Read More
Plasmon Enhanced Direct Bandgap Emissions in Cu7S4@Au2S@Au Nanorings
Nanostructured copper sulfides, promising earth-abundant p-type semiconductors, have found applications in a wide range of fields due to their versatility, tunable low bandgap, and environmental sustainability. The synthesis of hexagonal Cu7... -
Read More
Highly Efficient Fullerene-Free Polymer Solar Cells Fabricated with Polythiophene Derivative
A highly efficient fullerene-free polymer solar cell (PSC) based on PDCBT, a polythiophene derivative substituted with alkoxycarbonyl, has achieved an impressive power conversion efficiency of 10.16%, which is the best result in PSCs based o... -
Read More
Low-voltage organic devices based on pristine and self-assembled monolayer-treated HfTiOx gate dielectrics
Low-voltage organic field-effect transistors (OFETs) and complementary metal oxide semiconductor (CMOS) inverters based on pentacene and N,N′-ditridecylperylene-3,4,9,10-tetracarboxylic diimide (PTCDI-C13) were fabricated on HfTiOx gate diel... -
Read More
Higher Quantum State Transitions in Colloidal Quantum Dot with Heavy Electron Doping
Electron occupation in the lowest quantized state of the conduction band (1Se) in the colloidal quantum dot leads to the intraband transition in steady-state (1Se-1Pe). The intraband transition, solely originating from the quantum confinemen... -
Read More
High-harmonic generation: Drive round the twist
Light has long been used to detect the chirality of molecules but high-order harmonic generation now provides access to these chiral interactions on ultrafast timescales. http://www.nature.com/nphys/journal/v11/n8/full/nphys3395.html -
Read More
Gradients of Rectification: Tuning Molecular Electronic Devices by the Controlled Use of Different-Sized Diluents in Heterogeneous Self-Assembled Monolayers
Molecular electronics has received significant attention in the last decades. To hone performance of devices, eliminating structural defects in molecular components inside devices is usually needed. We herein demonstrate this problem can be ... -
Read More
Investigation of Charge Carrier Behavior in High Performance Ternary Blend Polymer Solar Cells
This study demonstrates high-performance, ternary-blend polymer solar cells by modifying a binary blend bulk heterojunction (PPDT2FBT:PC71BM) with the addition of a ternary component, PPDT2CNBT. PPDT2CNBT is designed to have complementary ab... -
Read More
Adsorption of Carbon Dioxide on Unsaturated Metal Sites in M2(dobpdc) Frameworks with Exceptional Structural Stability and Relation between Lewis Acidity and Adsorption Enthalpy
A series of metal–organic frameworks (MOFs) M2(dobpdc) (M=Mn, Co, Ni, Zn; H4dobpdc=4,4′-dihydroxy-1,1′-biphenyl-3,3′-dicarboxylic acid), with a highly dense arrangement of open metal sites along hexagonal channels were prepared by microwave-... -
Read More
Programmed activation of cancer cell apoptosis: A tumor-targeted phototherapeutic topoisomerase I inhibitor
We report here a tumor-targeting masked phototherapeutic agent 1 (PT-1). This system contains SN-38—a prodrug of the topoisomerase I inhibitor irinotecan. Topoisomerase I is a vital enzyme that controls DNA topology during replication, trans... -
Read More
Probing Distinct Fullerene Formation Processes from Carbon Precursors of Different Sizes and Structures
Fullerenes, cage-structured carbon allotropes, have been the subject of extensive research as new materials for diverse purposes. Yet, their formation process is still not clearly understood at the molecular level. In this study, we performe... -
Read More
Manifesting Subtle Differences of Neutral Hydrophilic Guest Isomers in a Molecular Container by Phase Transfer
Achieving strong host–guest interactions between synthetic hosts and hydrophilic guests in solution is challenging because solvation effects overwhelm other effects. To resolve this issue, we transferred complexes of cucurbit[7]uril (CB[7]) ...