Total Syntheses of Arcyriaflavin A and Calothrixin B Using 2,2′-Bisindole-3-acetic Acid Derivative as a Common Intermediate
| author | Cheol-Hong Cheon |
|---|---|
| journal | Org. Lett., 2017, 19 (11), pp 2785–2788 |
| Homepage | https://sites.google.com/site/cheonresearchlab/ |
| 첨부파일 '1' |
|---|
A new protocol for the synthesis of 2,2′-bisindole-3-acetic acid derivatives from aldimines derived from 2-aminocinnamic acid derivatives and indole-2-carboxaldehyde was developed via a cyanide-catalyzed imino-Stetter reaction. With this protocol, the divergent total syntheses of arcyriaflavin A, a representative indolocarbazole natural product, and calothrixin B, a representative indolo[3,2-j]phenanthridine natural product, were completed using a 2,2′-bisindole-3-acetic acid derivative as the common intermediate.
« Prev Collision Cross Sections and Ion Structures: Development of a...
Collision Cross Sections and Ion Structures: Development of a...
2017.10.12by
〈
Synthesis, Characterization, and Efficient Catalytic Activiti... Next »
Synthesis, Characterization, and Efficient Catalytic Activiti...
2017.09.26by
〉
-
Read More
Single Component Organic Solar Cells Based on Oligothiophene-Fullerene Conjugate
Han Young WooAdv. Functional Materials, 2017, 27(DOI: 10.1002/adfm.201702474)A new donor (D)–acceptor (A) conjugate, benzodithiophene-rhodanine–[6,6]-phenyl-C61 butyric acid methyl ester (BDTRh–PCBM) comprising three covalently linked blocks, one of p-type oligothiophene containing BDTRh moieties and two of n-type PC... -
Read More
Lanthanide metal-assisted synthesis of rhombic dodecahedral MNi (M=Ir and Pt) nanoframes toward efficient oxygen evolution catalysis
Kwangyeol LeeNano energy, 2017, Accepted Manuscript (https://doi.org/10.1016/j.nanoen.2017.10.033)Mixed metal alloy nanoframeworks have shown a great promise as electrocatalysts in water electrolyzers and fuel cells. Although a limited number of mixed metal alloy nanoframeworks have been synthesized through phase segregation of alloy pha... -
Read More
Radially Phase Segregated PtCu@PtCuNi Dendrite@Frame Nanocatalyst for the Oxygen Reduction Reaction
Kwangyeol LeeACS Nano, Just Accepted Manuscript(DOI: 10.1021/acsnano.7b04097)Pt-based alloy nanoframes have shown a great potential as electrocatalysts toward oxygen reduction reaction (ORR) in fuel cells. However, the intrinsically infirm nanoframes could be severely deformed during extended electro-cyclings, which ... -
Read More
Collision Cross Sections and Ion Structures: Development of a General Calculation Method via High-quality Ion Mobility Measurements and Theoretical Modeling
Hugh I. KimAnalyst, 2017, DOI: 10.1039/C7AN01276DIon mobility mass spectrometry (IM-MS) has become an important tool for the structural investigation of ions in the gas phase. Accurate theoretical evaluation of ion collision cross sections (CCSs) is essential for the effective application... -
Read More
Total Syntheses of Arcyriaflavin A and Calothrixin B Using 2,2′-Bisindole-3-acetic Acid Derivative as a Common Intermediate
Cheol-Hong CheonOrg. Lett., 2017, 19 (11), pp 2785–2788A new protocol for the synthesis of 2,2′-bisindole-3-acetic acid derivatives from aldimines derived from 2-aminocinnamic acid derivatives and indole-2-carboxaldehyde was developed via a cyanide-catalyzed imino-Stetter reaction. With this pro... -
Read More
Synthesis, Characterization, and Efficient Catalytic Activities of a Nickel(II) Porphyrin: Remarkable Solvent and Substrate Effects on Participation of Multiple Active Oxidants
Suk Joong LeeChem. Eur. J. 2017, 23, 11969 – 11976(DOI: 10.1002/chem.201702750)A new nickel(II) porphyrin complex, [NiII(porp)] (1), has been synthesized and characterized by 1H NMR, 13C NMR and mass spectrometry analysis. This NiII porphyrin complex 1 quantitatively catalyzed the epoxidation reaction of a wide range o... -
Read More
Molecular Insights into Human Serum Albumin as a Receptor of Amyloid-β in the Extracellular Region
Hugh I. KimJ. Am. Chem. Soc., Just Accepted Manuscript(DOI: 10.1021/jacs.7b08584)Regulation of amyloid-β (Aβ) aggregation by metal ions and proteins is essential for understanding the pathology of Alzheimer’s disease (AD). Human serum albumin (HSA), a regulator of metal and protein transportation, can modulate metal–A... -
Read More
Two Regioisomeric π-Conjugated Small Molecules: Synthesis, Photophysical, Packing and Optoelectronic Properties
Dong Hoon Choi, Han Young WooAdvanced Functional Materials, 27(33), n/a(2017) (DOI: 10.1002/adfm.201701942)Two regioisomeric D1-A-D-A-D1 type π-conjugated molecules (1,4-bis{5-[4-(5-fluoro-7-(5-hexylthiophen-2-yl)benzo[c][1,2,5]thiadiazole)]thiophen-2-yl}-2,5-bis(hexyldecyloxy)benzene (Prox-FBT) and 1,4-bis{5-[4-(6-fluoro-7-(5-hexylthiophen-2-yl... -
Read More
Major Electronic Transition Shift from Bandgap to Localized Surface Plasmon Resonance in CdxHg1-xSe Alloy Nanocrystals
Kwang Seob JeongChem. Mater., Just Accepted Manuscript(DOI: 10.1021/acs.chemmater.7b03813)CdxHg1-xSe alloy nanocrystals are obtained from CdSe semiconductor nanocrystals via cation exchange. By varying the composition during the exchange process, the CdxHg1-xSe alloy nanocrystals offer a widely tunable electronic transition from ... -
Read More
Rational Design of In Vivo Tau Tangle-Selective Near Infrared Fluorophores: Expanding the BODIPY Universe
Jong Seung KimJ. Am. Chem. Soc., Just Accepted Manuscript(DOI:10.1021/jacs.7b05878)The elucidation of the cause of Alzheimer’s disease remains one of the greatest questions in neurodegenerative research. The lack of highly reliable low-cost sensors to study the structural changes in key proteins during the progres-sion of ... -
Read More
Achieving Highly Efficient Nonfullerene Organic Solar Cells with Improved Intermolecular Interaction and Open-Circuit Voltage
Han Young WooAdv. Mater. 2017, in press.(DOI: 10.1002/adma.201700254)A new acceptor–donor–acceptor-structured nonfullerene acceptor ITCC (3,9-bis(4-(1,1-dicyanomethylene)-3-methylene-2-oxo-cyclopenta[b]thiophen)-5,5,11,11-tetrakis(4-hexylphenyl)-dithieno[2,3-d′:2,3-d′]-s-indaceno[1,2-b:5,6-b′]-dithiophene) is... -
Read More
Ionic effect on the excited-state proton transfer reactions in aqueous solutions
Sungnam ParkPhys. Chem. Chem. Phys., Accepted Manuscript (2017) (DOI:10.1039/C7CP04392A)Proton dissociation (PD) reactions of weak acids and proton transfer (PT) processes in aqueous solution are strongly influenced by ions. However, a detailed molecular picture that describes how ions affect the rates for PD and PT processes i... -
Read More
A conductive porous organic polymer with superprotonic conductivity of a Nafion-type electrolyte
Chang Seop HongJ. Mater. Chem. A, 2017, 5, 17492-17498(DOI: 10.1039/C7TA05279K)As potential solid electrolytes in fuel cells, porous organic polymers show compelling proton conductivities (up to ∼10−2 S cm−1), but even higher performance is required for real applications. In this work, we prepared a biphenyl-based orga... -
Read More
Quantum optical measurements with undetected photons through vacuum field indistinguishability
Minhaeng ChoSci Rep. 2017; 7: 6558.(doi: 10.1038/s41598-017-06800-0)Quantum spectroscopy and imaging with undetected idler photons have been demonstrated by measuring one-photon interference between the corresponding entangled signal fields from two spontaneous parametric down conversion (SPDC) crystals. In ... -
Read More
Nanoscale Control of Amyloid Self-Assembly Using Protein Phase Transfer by Host-Guest Chemistry
Hugh I. KimScientific Reports, 2017, 7, 5710Amyloid fibrils have recently been highlighted for their diverse applications as functional nanomaterials in modern chemistry. However, tight control to obtain a targeted fibril length with low heterogeneity has not been achieved because of ... -
Read More
A Mitochondria-targeted Cryptocyanine-Based Photothermogenic Photosensitizer
Jong Seung KimJ. Am. Chem. Soc. 9972-9978, 139, 2017.Cryptocyanine-based probes exhibit highly efficient photothermal conversion and represent a new class of photothermal agents for use in photothermal therapy (PTT). With the thermal susceptibility of mitochondria in mind, we have prepared a m... -
Read More
Cell imaging: An intracellular dance visualized
Sang-Hee ShimNature 546, 39–40 (doi:10.1038/nature22500)The development of a microscopy technique that enables observation of the interactions between six types of organelle, in 3D and over time, holds promise for improving our understanding of intracellular processes. See Letter p.162 http... -
Read More
High-efficiency photovoltaic cells with wide optical band gap polymers based on fluorinated phenylene-alkoxybenzothiadiazole
Han Young WooEnergy Environ. Sci., 2017, Advance Article(DOI:10.1039/C6EE03051C)A series of semi-crystalline, wide band gap (WBG) photovoltaic polymers were synthesized with varying number and topology of fluorine substituents. To decrease intramolecular charge transfer and to modulate the resulting band gap of D–A type... -
Read More
Eco-Friendly Solvent-Processed Fullerene-Free Polymer Solar Cells with over 9.7% Efficiency and Long-Term Performance Stability
Dong Hoon ChoiAdv. Energy Mater. 2017 (DOI: 10.1002/aenm.201700566)A wide-bandgap polymer, (poly[(2,6-(4,8-bis(5-(2-ethylhexyl)thiophen-2-yl)-benzo[1,2-b:4,5-b′]dithiophene))-alt-(2,5-(methyl thiophene carboxylate))]) (3MT-Th), is synthesized to obtain a complementary broad range absorption when harmonized ... -
Read More
Iridium-Based Multimetallic Nanoframe@Nanoframe Structure: An Efficient and Robust Electrocatalyst toward Oxygen Evolution Reaction
Kwangyeol LeeACS Nano, Just Accepted Manuscript(DOI: 10.1021/acsnano.7b00233)Nanoframe electrocatalysts have attracted a great interest due to their inherently high active surface area per a given mass. Although recent progress has enabled the preparation of single nanoframe structures with a variety of morphologies,...
Designed by sketchbooks.co.kr / sketchbook5 board skin